Influx wrote:One of the few biologists to propose a radically novel approach to these questions is Dr Rupert Sheldrake. In his book A New Science of Life Sheldrake rejected the idea that the brain is a warehouse for memories and suggested it is more like a radio receiver for tuning into the past. Memory is not a recording process in which a medium is altered to store records, but a journey that the mind makes into the past via the process of morphic resonance.
Cryptochromes—a potential magnetoreceptor: what do we know and what do we want to know?
Miriam Liedvogel1,2,* and Henrik Mouritsen1
Cryptochromes have been suggested to be the primary magnetoreceptor molecules underlying light-dependent magnetic compass detection in migratory birds. Here we review and evaluate (i) what is known about these candidate magnetoreceptor molecules, (ii) what characteristics cryptochrome molecules must fulfil to possibly underlie light-dependent, radical pair based magnetoreception, (iii) what evidence supports the involvement of cryptochromes in magnetoreception, and (iv) what needs to be addressed in future research. The review focuses primarily on our knowledge of cryptochromes in the context of magnetoreception.
Cryptochrome A photoreceptor with the properties of a magnetoreceptor?
Thorsten Ritz,1 T Yoshii,2 C Helfrich-Foerster,2 and Margaret Ahmad3
It was recently discovered that the photoreceptor cryptochrome is involved in mediating magnetosensitive entrainment of the internal clock of fruit flies.1 This discovery follows other recent studies implicating a role of cryptochrome in mediating magnetic sensitivity in orientation responses of fruit flies2,3 and growth responses of plants.4 Such widespread use of the same molecule for mediating magnetic sensitivity might suggest that cryptochrome is in some way optimal for detecting the magnetic field of the earth and that the magnetoreception function cannot be easily taken over by other molecules. This raises the question what properties might set cryptochromes apart from other molecules in terms of their ability to detect the geomagnetic field. Here, we will discuss possible answers to this question.
Cryptochromes
M Ahmad - Annual Review of Plant Biology, 2011 - annualreviews.org
... Note that dark and signaling states in cryptochromes are not firmly established. hυ indicates
photon absorption; +e − , electron donation to the FAD via the electron transfer chain (shown
in Figure 5); +H + , protonation of FAD° − ; and ET, electron transfer from FAD to a substrate. ...
Human cryptochrome exhibits light-dependent magnetosensitivity
Lauren E. Foley,1 Robert J. Gegear1, 2 & Steven M. Reppert1
Journal name: Nature Communications
Volume: 2,Article number:356DOI:doi:10.1038/ncomms1364
Published21 June 2011
Humans are not believed to have a magnetic sense, even though many animals use the Earth's magnetic field for orientation and navigation. One model of magnetosensing in animals proposes that geomagnetic fields are perceived by light-sensitive chemical reactions involving the flavoprotein cryptochrome (CRY). Here we show using a transgenic approach that human CRY2, which is heavily expressed in the retina, can function as a magnetosensor in the magnetoreception system of Drosophila and that it does so in a light-dependent manner. The results show that human CRY2 has the molecular capability to function as a light-sensitive magnetosensor and reopen an area of sensory biology that is ready for further exploration in humans.
Biofizika. 1998 Jul-Aug;43(4):632-9.
[Magnetic storms as a stress factor].
[Article in Russian]
Rapoport SI, Boldypakova TD, Malinovskaia NK, Oraevskiĭ VN, Meshcheriakova SA, Breus TK, Sosnovskiĭ AM.
SourceSechenov Medical Academy, Moscow, Russia.
Abstract
The functional characteristics variations during the magnetic storms were observed in both the healthy humans and in patients with cardio-vascular diseases as well as in cosmonauts at SOYUZ spacecraft and MIR station. These characteristics revealed a nonspecific adaptive stress reaction, which should be accompanied by the variations in the stress-hormone production rate. The neurohumoral regulation of the organism functions during the geomagnetic storms in a group of patients with cardio-vascular pathology and in a control group of healthy individuals were studied. The magnetic storm effect characterised of both the sick and healthy examines was the violated ratio of glucocorticoids and mineralocorticoids, namely increase of cortisone secretion (adrenal cortex hormone), as well as some tendency to the activation of sympathoadrenal system. Our investigations revealed also a suppressed production of melatonin (the pineal gland hormone) during the geomagnetic storm. These results are not in contradictions with the functional characteristics violation by the magnetic storms and correspond to the existence of adaptive stress reaction of the human organism to the geomagnetic field disturbances.
Would aspects of dreaming then fall into a related bucket with proposed "Remote Viewing"? The "mode" aspect of dreaming simply be a function between transmitter and receiver? 10-19
Magnetic fields produced by steady currents in the body
DAVID COHEN*, YORAM PALTIt, B. NEIL CUFFIN*, AND STEPHEN J. SCHMID**
..."The source associated with each follicle can therefore be considered as a current dipole pointing along the follicle into the root and located either within or near the follicle. If within, then this source could be, for example, equivalent to a polarized layer lining the follicle, with negative charges on the inside.
One idea, as presented on the thread, is completely absurd. That of the brain being an antenna that receives consciousness. This idea is somehow proven by the fact that some people have lived fairly normal lives while missing all or significant portions of their brains. I do not deny the possibility that the brain might have some as of yet undiscovered radio like abilities.
Reaction Kinetics and Mechanism of Magnetic Field Effects in Cryptochrome
Ilia Solov'yov and Klaus Schulten
J. Phys. Chem. B, Just Accepted Manuscript
DOI: 10.1021/jp209508y
Publication Date (Web): December 15, 2011
Abstract
Creatures as varied as mammals, fish, insects, reptiles, and birds have an intriguing `sixth' sense that allows them to orient themselves in the Earth's magnetic field. Despite decades of study, the physical basis of this magnetic sense remains elusive. A likely mechanism is furnished by magnetically sensitive radical pair reactions occurring in the retina, the light-sensitive part of animal eyes. A photoreceptor, cryptochrome, has been suggested to endow birds with magnetoreceptive abilities as the protein has been shown to exhibit the biophysical properties required for an animal magnetoreceptor to operate properly. Here, we propose a theoretical analysis method for identifying cryptochrome's signaling reactions involving comparison of measured and calculated reaction kinetics in cryptochrome. Application of the method yields an exemplary light-driven reaction cycle, supported through transient absorption and electron-spin-resonance observations together with known facts on avian magnetoreception. The reaction cycle permits one to predict magnetic field effects on cryptochrome activation and deactivation. The suggested analysis method gives insight into structural and dynamic design features required for optimal detection of the geomagnetic field by cryptochrome and suggests further experimental and theoretical studies.
Can Humans Sense Earth's Magnetism? Human Retina Protein Can Function as Light-Sensitive Magnetic Sensor
ScienceDaily (June 21, 2011) — For migratory birds and sea turtles, the ability to sense Earth's magnetic field is crucial to navigating the long-distance voyages these animals undertake during migration. Humans, however, are widely assumed not to have an innate magnetic sense. Research published in Nature Communications this week by faculty at the University of Massachusetts Medical School shows that a protein expressed in the human retina can sense magnetic fields when implanted into Drosophila, reopening an area of sensory biology in humans for further exploration.
To test whether the human cryptochrome 2 protein (hCRY2) has a similar magnetic sensory ability, Steven Reppert, MD, the Higgins Family Professor of Neuroscience and chair and professor of neurobiology, graduate student Lauren Foley, and Robert Gegear, PhD, a post doctoral fellow in the Reppert lab now an assistant professor of biology and biotechnology at Worcester Polytechnic Institute, created a transgenic Drosophila model lacking its native cryptochrome protein but expressing hCRY2 instead. Using a behavioral system Reppert's group previously developed, they showed that these transgenic flies were able to sense and respond to an electric-coil-generated magnetic field and do so in a light-dependent manner.
These findings demonstrate that hCRY2 has the molecular capability to function in a magnetic sensing system and may pave the way for further investigation into human magnetoreception. "Additional research on magneto sensitivity in humans at the behavioral level, with particular emphasis on the influence of magnetic field on visual function, rather than non-visual navigation, would be informative," wrote Reppert and his colleagues in the study. http://www.sciencedaily.com/releases/20 ... 121319.htm
Biofizika. 1998 Jul-Aug;43(4):632-9.
Magnetic storms as a stress factor
[Article in Russian]
Rapoport SI, Boldypakova TD, Malinovskaia NK, Oraevskiĭ VN, Meshcheriakova SA, Breus TK, Sosnovskiĭ AM.
SourceSechenov Medical Academy, Moscow, Russia.
Abstract
The functional characteristics variations during the magnetic storms were observed in both the healthy humans and in patients with cardio-vascular diseases as well as in cosmonauts at SOYUZ spacecraft and MIR station. These characteristics revealed a nonspecific adaptive stress reaction, which should be accompanied by the variations in the stress-hormone production rate. The neurohumoral regulation of the organism functions during the geomagnetic storms in a group of patients with cardio-vascular pathology and in a control group of healthy individuals were studied. The magnetic storm effect characterised of both the sick and healthy examines was the violated ratio of glucocorticoids and mineralocorticoids, namely increase of cortisol secretion (adrenal cortex hormone), as well as some tendency to the activation of sympathoadrenal system. Our investigations revealed also a suppressed production of melatonin (the pineal gland hormone) during the geomagnetic storm. These results are not in contradictions with the functional characteristics violation by the magnetic storms and correspond to the existence of adaptive stress reaction of the human organism to the geomagnetic field disturbances.
tolenio wrote:Ignorance and mistakes ares not absurdity, they are simply ignorance and mistakes.
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